Skip to content
lunerievidence engine
Sign inCreate free account

01Markers · Lipids

Triglycerides

The most common type of fat in the body. The test measures triglycerides carried in the blood, usually after a fast, because a meal raises them for several hours.

Measured in
Blood (serum)
Units
mg/dL, mmol/L
Also called
TG, triacylglycerols
  1. L-carnitine
  2. Berberine
  3. HIIT
  4. Collagen
  5. Magnesium
  6. Milk thistle
  7. Zinc
  8. Melatonin
  9. Zone 2 cardio
  10. Taurine
  11. Vitamin C
  12. Ubiquinol (CoQ10)
  13. Red yeast rice
  14. Omega-3
  15. Creatine
  16. Ashwagandha
  17. Iron
  18. NAC
  19. Finnish sauna
  20. Vitamin E
  21. Vitamin D3
  22. NAD+
  23. Vitamin K2
  24. L-theanine
  25. Resveratrol
  26. Lion's mane
  27. PQQ
Triglycerides across the 27 supplements and practices researched so far · best evidence first

AWhat moves Triglycerides

26 of 27 studied

In human studies, 19 of the 27 supplements and practices researched so far lowered triglycerides. 5 showed no change and 2 had mixed results. 1 was never studied for it.
  • Supported 19
  • No effect 5
  • Conflicting 2
  • Not studied 1
See Triglycerides on the evidence map →Check claims about Triglycerides →

Moves it19

Human studies found a change. The grade reflects the studies behind it, from A (strongest) to D.

L-carnitineLowersGrade A

L-carnitine lowers triglycerides.

Meta-analysis or review · Moderate effect · 69 studies linked

Studied in: General adult, T2DM, CKD, Dyslipidemia

333 studies in corpus — strongest evidence domain. Consolidated with triglycerides entry. Multiple meta-analyses confirm direction and magnitude. Animal contradiction: Talari 2019 (PLC, DIO mice) showed no TG reduction (ns) despite TC improvement — PLC vs LC form difference or short duration may explain. Preserved a...

Open the L-carnitine page →Check a claim about this →
BerberineLowersGrade A

Berberine lowers triglycerides.

53 studies linked

Studied in: Dyslipidemia, T2DM, Metabolic syndrome, Predominantly Chinese RCTS

Open the Berberine page →Check a claim about this →
HIITLowersGrade A

HIIT lowers triglycerides.

Meta-analysis or review · 51 studies linked

Studied in: Overweight obese, T2DM, Metabolic syndrome, Children adolescents

Open the HIIT page →Check a claim about this →
CollagenLowersGrade A

Collagen lowers triglycerides.

Meta-analysis or review · 42 studies linked

Studied in: Adult mixed sex, Cardiometabolic risk, Metabolic syndrome

Open the Collagen page →Check a claim about this →
MagnesiumLowersGrade A

Magnesium lowers triglycerides.

Meta-analysis or review · Small effect · 26 studies linked

Studied in: Dyslipidemic, Metabolic syndrome, General adult

Open the Magnesium page →Check a claim about this →
Milk thistleLowersGrade A

Milk thistle lowers triglycerides.

Meta-analysis or review · Small to moderate effect · 26 studies linked

Studied in: NAFLD, Metabolic syndrome, Type 2 diabetes, Hypertriglyceridemia

Approximately −0.38 SMD; −15 to −35 mg/dL in NAFLD populations. Most significant reduction with baseline hypertriglyceridemia; null in normolipidemic populations. Contested (see pc_005).

Open the Milk thistle page →Check a claim about this →
ZincLowersGrade A

Zinc lowers triglycerides.

Meta-analysis or review · 23 studies linked

Studied in: T2D, Hypertriglyceridemia, Metabolic syndrome, Adults

TG reduction stronger in T2D and metabolic syndrome. Likely mediated partly via improved insulin sensitivity reducing hepatic de novo lipogenesis and VLDL secretion.

Open the Zinc page →Check a claim about this →
MelatoninLowersGrade A

Melatonin lowers triglycerides.

Meta-analysis or review · Small effect · 15 studies linked

Studied in: Adults, Metabolic syndrome, NASH

High heterogeneity; may be secondary to hepatic lipid handling improvement

Open the Melatonin page →Check a claim about this →
Zone 2 cardioLowersGrade A

Zone 2 cardio lowers triglycerides.

Meta-analysis or review · 11 studies linked

Studied in: Adults overweight obese, Adults dyslipidemia

Open the Zone 2 cardio page →Check a claim about this →
TaurineLowersGrade A

Taurine lowers triglycerides.

Meta-analysis or review · 10 studies linked

Studied in: Hypertriglyceridemia, Metabolic syndrome, Overweight obese, Adults

89 corpus studies — highest lipid biomarker coverage. Multiple MAs confirm.

Open the Taurine page →Check a claim about this →
Vitamin CLowersGrade A

Vitamin C lowers triglycerides.

Meta-analysis or review · 10 studies linked

Studied in: Adults, Elevated triglycerides at baseline, Mixed cardiometabolic

Open the Vitamin C page →Check a claim about this →
Ubiquinol (CoQ10)LowersGrade A

Ubiquinol (CoQ10) lowers triglycerides.

Meta-analysis or review · 5 studies linked

Studied in: Dyslipidemia, Metabolic syndrome

Open the Ubiquinol (CoQ10) page →Check a claim about this →
Red yeast riceLowersGrade A

Red yeast rice lowers triglycerides.

2 studies linked

Studied in: Primary HCH, Statin intolerant, Metabolic syndrome, Elevated TG

Open the Red yeast rice page →Check a claim about this →
Omega-3LowersGrade A

Omega-3 lowers triglycerides.

Large effect · 0 studies linked

This result is graded, but no study is linked to it yet. Treat it as unconfirmed.

Studied in: General adult, Hypertriglyceridemia, Metabolic syndrome, T2DM

Most replicated effect of omega-3 supplementation; 669 studies in corpus; FDA-approved indication at 4g/day (Vascepa, Lovaza)

Open the Omega-3 page →Check a claim about this →
CreatineLowersGrade B

Creatine lowers triglycerides.

Human trials · 4 studies linked

Open the Creatine page →Check a claim about this →
AshwagandhaLowersGrade B

Ashwagandha lowers triglycerides.

Meta-analysis or review · 3 studies linked

Studied in: Stressed adults, Overweight adults, Type2 diabetes, Indian cohorts

Open the Ashwagandha page →Check a claim about this →
IronLowersGrade B

Iron lowers triglycerides.

Human trials · 1 study linked

Studied in: General

No established effect of iron supplementation on triglycerides.

Open the Iron page →Check a claim about this →
NACLowersGrade B

NAC lowers triglycerides.

Small effect · 1 study linked

Studied in: Metabolic syndrome

Open the NAC page →Check a claim about this →
Finnish saunaLowersGrade C

Finnish sauna lowers triglycerides.

Human trials · 1 study linked

Studied in: General adult

Open the Finnish sauna page →Check a claim about this →

Studied, no change5

Studies looked and found no meaningful change. That is a result, not missing data.

Vitamin ENo changeGrade A

Studies of Vitamin E found no change in triglycerides.

44 studies linked

Studied in: Adult, Mixed sex, NAFLD, NASH

WMD −0.09 mmol/L (ns) across meta-analyses. Consistent null across VE-MA-002, VE-MA-004, corey_2015, ahmadi_2014. Grade A null finding.

Open the Vitamin E page →Check a claim about this →
Vitamin D3No changeGrade A

Studies of Vitamin D3 found no change in triglycerides.

Meta-analysis or review · Negligible effect · 3 studies linked

Studied in: Deficient baseline, Metabolic syndrome, Young adults, Asian

Direction corrected from 'decrease' to 'no_change'. Wang 2012 MA (n=1346, 12 RCTs, grade A) found NO significant effect on triglycerides. Chen 2016 (n=28, uncontrolled) insufficient to override controlled MA null finding.

Open the Vitamin D3 page →Check a claim about this →
NAD+No changeGrade A

Studies of NAD+ found no change in triglycerides.

1 study linked

Studied in: Healthy, Overweight, Age 40 60

Open the NAD+ page →Check a claim about this →
Vitamin K2No changeGrade B

Studies of Vitamin K2 found no change in triglycerides.

Meta-analysis or review · 2 studies linked

Studied in: General adult, Healthy, European

Consolidated with triglycerides entry. Hartley 2015: null. 7 studies in corpus — no positive directional signal.

Open the Vitamin K2 page →Check a claim about this →
L-theanineNo changeGrade B

Studies of L-theanine found no change in triglycerides.

Human trials · 1 study linked

Studied in: Elderly japanese, Green tea mixture not pure ltheanine

Same grade inconsistency as fasting_glucose.

Open the L-theanine page →Check a claim about this →

Mixed results2

Studies disagree, or the direction depends on who was studied.

ResveratrolMixed resultsGrade A

Studies of Resveratrol and triglycerides disagree.

Meta-analysis or review · Small effect · 53 studies linked

Studied in: Obese, Metabolic syndrome, Hypertriglyceridemia, Dyslipidemia

See triglycerides entry for detailed analysis. Merged: tg and triglycerides refer to same biomarker.

Open the Resveratrol page →Check a claim about this →
Lion's maneMixed resultsGrade C

Studies of Lion's mane and triglycerides disagree.

Human trials · 1 study linked

Studied in: Healthy volunteers, Asian, Short term, Pilot

Lipid panel measured in Xiao-qian 2021 pilot; direction not extractable

Open the Lion's mane page →Check a claim about this →

Not studied1

No usable human study has measured Triglycerides with these. A gap is not a negative result: nobody has looked.

PQQ

Commission research on a gap →

Why trials measure it. They respond quickly to changes in diet, so omega-3 and nutrition trials report them often.

About this marker: Triglycerides Test (MedlinePlus, U.S. National Library of Medicine).

Evidence states come from published human studies found in PubMed and OpenAlex and read by a model pipeline. "Not studied" means no usable human study was found for this marker, which is a gap, not a negative result. Every result links its studies so you can check it.

Research summary for education. Not medical advice.