Research Library
Free users can browse compounds, synopsis copy, and dossier openings here. Upgrade to the Research plan to unlock biomarkers, evidence tables, dosing, PGx, and compare-ready detail.
Coverage
Research entries mapped
27
Canonical dossiers available for live research review.
Biomarkers
Biomarker-linked entries
27
Entries with human-linked marker coverage users can actually act on.
Claims
Evidence-graded signals
2399
Signals with explicit grading rather than unsupported promise language.
Literature
Literature-tracked entries
27
Research objects with enough study depth or recency to review with confidence.
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Search across compound aliases, subtitles, and taglines before narrowing by section.
Research opens the decision-grade dossier layer
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Curated research desk
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Creatine
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NAC
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Magnesium
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Creatine
Monohydrate
Strength · Cognitive performance
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NAC
N-Acetyl Cysteine
Liver protection · Glutathione synthesis
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HIIT Training
behavioral intervention
cardiovascular fitness · fat loss · metabolic health
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Omega 3
EPA + DHA
Triglycerides · Inflammation · CV risk
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Magnesium
Glycinate and L-Threonate
Insulin sensitivity, sleep, and muscle function
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Vitamin D3
Structured dossier entry
1,25-dihydroxyvitamin D3 binds VDR; VDR heterodimerises with RXR; complex translocates to nucleus and binds vitamin D response elements (VDREs) in promoter regions of >1000 target genes regulating calcium homeostasis, immune function, cell proliferation, and apoptosis
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Zinc
Structured dossier entry
Pancreatic beta-cell zinc co-crystallization with insulin hexamers; zinc required for regulated insulin granule storage and secretion via ZnT8 (SLC30A8) transporter; zinc deficiency impairs insulin processing and secretion
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Zone 2 Cardio
behavioral intervention
mitochondrial biogenesis · fat oxidation · aerobic base
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Ubiquinol
Reduced CoQ10
Mitochondrial electron transport & antioxidant defence
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Red Yeast Rice
Structured dossier entry
Monacolin K (structurally identical to lovastatin) competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, reducing hepatic cholesterol production and upregulating LDLR expression via SREBP-2 activation
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Vitamin C
Structured dossier entry
Direct ROS scavenging — ascorbate donates electrons to neutralize superoxide, hydroxyl radicals, and peroxynitrite; oxidized to dehydroascorbic acid (DHA), which is recycled back to ascorbate via glutathione-dependent reductase, coupling vitamin C status to cellular glutathione pool
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Berberine
HCl Extract
Blood glucose · LDL · Gut microbiome
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Iron
Structured dossier entry
Heme biosynthesis — iron incorporated into protoporphyrin IX by ferrochelatase to form heme; heme assembles with globin chains to produce functional hemoglobin in erythroid precursors
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L Theanine
Free amino acid
Alpha-wave support · calm focus · sleep quality
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Melatonin
Structured dossier entry
MT1/MT2 receptor agonism → Gi protein coupling → cAMP suppression → SCN circadian phase shift
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Ashwagandha
Standardized root extract
Cortisol reduction · stress resilience · recovery support
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Finnish Sauna
environmental intervention
cardiovascular health · longevity · recovery
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Vitamin K2
Structured dossier entry
Carboxylation of osteocalcin (OCN) via gamma-glutamyl carboxylase (GGCX); converts undercarboxylated osteocalcin (ucOC) to carboxylated osteocalcin (cOC), enabling calcium binding in bone matrix hydroxyapatite
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L Carnitine
Structured dossier entry
Long-chain fatty acid mitochondrial transport via carnitine palmitoyltransferase I/II (CPT-I/CPT-II) — L-carnitine forms acylcarnitine esters enabling translocation of acyl groups across the inner mitochondrial membrane for beta-oxidation
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NAD+
Dietary Supplement
Oral NR/NMN → gut absorption → NRK1/NAMPT salvage enzymes → intracellular NAD+ elevation in blood, muscle, and adipose tissue
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Resveratrol
Structured dossier entry
AMPK activation → increased NAD+/NADH ratio → SIRT1 deacetylase activation
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Vitamin E
Structured dossier entry
Lipid peroxidation chain-breaking — alpha-tocopherol donates hydrogen to lipid peroxyl radicals (LOO•), terminating radical chain reactions in cell membranes and LDL particles
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Taurine
Free amino acid
Osmotic regulation · cardiac function · recovery support
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Collagen
Structured dossier entry
Fibroblast Collagen Synthesis — Dipeptide Signaling
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Milk Thistle
Structured dossier entry
Direct ROS scavenging via flavonolignan electron donation — silybin B phenolic OH groups quench hydroxyl, superoxide, and peroxynitrite radicals at nanomolar concentrations in vitro
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Lion's Mane
Hericium Extract
NGF support, memory, and neuroprotection
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PQQ
Pyrroloquinoline Quinone
Mitochondrial biogenesis and neuroprotection
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Ezetimibe
Cholesterol Absorption Inhibitor
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Fibrates
PPARα Agonists
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GLP 1 Agonists
Incretin Mimetics (Semaglutide / Liraglutide)
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Levothyroxine
Synthetic T4 Thyroid Hormone
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Metformin
Biguanide Antidiabetic
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Niacin (Rx)
Extended-Release Niacin
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PCSK9 Inhibitors
Monoclonal Antibodies (Evolocumab / Alirocumab)
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Proton Pump Inhibitors
H+/K+-ATPase Inhibitors (Omeprazole / Pantoprazole)
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Statins
HMG-CoA Reductase Inhibitors
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Resistance Training
Progressive Overload Protocol
Strongest lifestyle intervention for metabolic and hormonal biomarker optimisation
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Cold Water Immersion
Deliberate Cold Exposure (≤15°C)
Strong acute norepinephrine release; emerging evidence for inflammatory and metabolic benefits
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Time-Restricted Eating
16:8 Intermittent Fasting Protocol
Circadian alignment strategy with consistent metabolic improvements independent of caloric restriction
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Sleep Optimisation
7–9 Hours · Consistent Circadian Schedule
Most impactful recovery intervention; poor sleep dysregulates cortisol, testosterone, and glucose
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Protein Adequacy
Target Intake & Distribution (0.7–1g/lb)
Prerequisite for hormone synthesis, muscle preservation, and IGF-1 signalling
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